Psilocybe Caerulipes

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Psilocybe Caerulipes commonly known as blue-foot, is a rare psilocybin mushroom of the family Hymenogastraceae, [1] having psilocybin and psilocybin as main active compounds. An older synonym is Agaricus caerulipes.

It is in the section Semilanceatae, other members of the section include Psilocybe bohemicaPsilocybe callosaPsilocybe carbonariaPsilocybe cyanofibrillosaPsilocybe fimetariaPsilocybe indicaPsilocybe liniformans var. liniformansPsilocybe liniformans var. americanaPsilocybe pelliculosaPsilocybe semiinconspicuaPsilocybe semilanceataPsilocybe serbicaPsilocybe 

Psilocybe Caerulipes Medical usage

There have been calls for medical investigation of the use of synthetic and Psilocybe Caerulipes-derived psilocybin for the development of improved treatments of various mental conditions, including chronic cluster headaches,[18] following numerous anecdotal reports of benefits. There are also several accounts of psilocybin mushrooms sending both obsessive-compulsive disorders (“OCD”) and OCD-related clinical depression (both being widespread and debilitating mental health conditions) into complete remission immediately and for months at a time, compared to current medications which often have both limited efficacy[19] and frequent undesirable side-effects.[20] One such study states:

“Developing drugs that are more effective and faster acting for the treatment of OCD is of utmost importance and until recently, little hope was in hand. A new potential avenue of treatment may exist. There are several reported cases concerning the beneficial effects of hallucinogenic drugs (psilocybin and LSD), potent stimulators of 5-HT2A and 5-HT2C receptors, in patients with OCD (Brandrup and Vanggaard, 1977, Rapoport, 1987, Moreno and Delgado, 1997) and related disorders such as body dysmorphic disorder (Hanes, 1996)” [20]
“[I]f it can be established that this class of drug can indeed lead to rapid and substantial reduction in OCD symptoms, then it opens the way for a variety of future studies with new drugs that might possibly have the anti-OCD but not the psychedelic effects. […] Psilocybin, LSD, and mescaline are extremely potent agonists at 5-HT2A and 5-HT2C receptors and their binding potency to these receptors is correlated with their human potency as hallucinogens (Glennon et al., 1984). The acute improvement in symptoms described in the published case reports (Brandrup and Vanggaard, 1977, Rapoport, 1987, Moreno and Delgado, 1997) suggests that interactions with 5-HT2A and 5-HT2C receptors may be an essential component of anti-OCD drug action. The observations that administration of the non-selective 5-HT antagonists metergoline or ritanserin exacerbate OCD symptoms further supports this view.” [20]

silvaticaPsilocybe subfimetaria and Psilocybe venenata.

Dosage

Dosage of mushrooms containing Psilocybe Caerulipes depends on the potency of the mushroom (the total psilocybin and psilocybin content of the mushrooms), which varies significantly both between species and within the same species, but is typically around 0.5-2% of the dried weight of the mushroom. A typical dose of the rather common species, Psilocybe cubensis, is approximately 1 to 2 grams,[21] corresponding with 10 to 25 milligrams psilocybin and psilocybin, while about 2½ to 5 grams[21] dried material or 25 to 50 milligrams of psilocybin/psilocybin is considered a heavy dose. Fresh mushrooms are approximately 90% water. Drying the mushrooms breaks down the psilocybin much faster, thus shifting the psilocybin/psilocybin ratio. Exposure to heat generally breaks down the psychoactive ingredients. When eaten dry, 1 to 1.5 grams of mushrooms provide a small “trip” that can last up to 3 hours. The effects then are relatively mild, depending on the tolerance of the subject. With 3 to 3.5 grams one experiences a strong and solid trip which can last more than 3 hours.

Effects

When Psilocybe Caerulipes is ingested, it is broken down to produce psilocybin, which is responsible for the hallucinogenic effects.[7]

As with many psychoactive substances, the effects of psychedelic mushrooms are subjective and unpredictable. A common misconception, even seen in the professional environment, is that the effects experienced from psilocybin are due to a poisonous nature of the compound, yet the National Institute for Occupational Safety and Health, a branch of the Center for Disease Control, rated psilocybin less toxic than Aspirin.[8] The intoxicating effects of psilocybin-containing mushrooms typically last anywhere from 3 to 7 hours depending on dosage, preparation method and personal metabolism.[9][10]

The experience is typically inwardly oriented, with strong visual and auditory components. Visions and revelations may be experienced,[9] and the effect can range from exhilarating to distressing. There can be also a total absence of effects, even with large doses. This depends on the species (and to a much lesser degree the strain) of mushroom, substrate they grew from, the quality of the yield and conditions of growth.

As with other psychedelics such as LSD, the experience, or “trip,” is strongly dependent upon set and setting. A negative environment could likely induce a bad trip, whereas a comfortable and familiar environment would allow for a pleasant experience. [11]

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