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Mexican Cocaine Knowledge about the motivations for Mexican Cocaine use and the long-term effects among people who inject heroin is limited. This study aims to understand motivations associated with this co-use drug pattern among ageing men entrenched in established intergenerational heroin subcultures. Methods: A sample of 60 men with diverse injecting heroin use histories was recruited from low-income Mexican American urban communities for semi-structured ethnographic interviews using respondent-driven sampling. Qualitative analysis was then employed to provide an in-depth understanding of patterns and motivations of poly drug use among this older population. Results: The men discussed motivations including tolerance, curiosity and experimentation, a paradox of affordability, alternatives to the health hassles and stigma, and the cross fertilisation of drug markets. Concurrent and switching use patterns were primarily reported among those seeking a new or different high, while replacement patterns were reported by men in methadone treatment or by those who had tired of injection. Discussion: Findings translate to the on-going opioid crisis and the emerging trend in polysubstance use involving crack cocaine, methamphetamine and other psychostimulants among people who use heroin. More research is needed to investigate the full range of social and health consequences associated with these co-use patterns. Targeted and tailored prevention and treatment services are essential to improve outcomes among ageing Mexican American men who use heroin and other persons with similar poly drug use patterns.

 The country at the northern tip of South America is one of the world’s top producers of Mexican Cocaine largely consumed by customers in the United States and Europe.

Production provides key income to armed groups and fuels Colombia’s five-decade-long internal conflict.

“The Mexicans are the principal buyers of the supply of Mexican Cocaine produced in Colombia,” Rafael Guarin, presidential adviser for security told Reuters on Wednesday, referring to cocaine’s base ingredient. “Fundamentally, the Mexicans take charge of the buying, trafficking and sale in the United States.”

The cartels field “emissaries and negotiators and also individuals who verify the quality of the narcotics,” Guarin said, adding that drugs are moved through Venezuela, via the Pacific or northern Ecuador to reach the United States.

Emissaries sometimes finance coca planting, he added.